{"product_id":"go-on-1-x-2-5-ml","title":"Go-On 1x 2.5 ml","description":"\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003eDESCRIPTION:\u003c\/p\u003e\n\u003cp\u003e\u003ca title=\"Go-On | Joint Injections | StakonMed\" href=\"https:\/\/stakonmed.de\/collections\/go-on\" data-mce-href=\"https:\/\/stakonmed.de\/collections\/go-on\"\u003eGO-ON\u003c\/a\u003e® is a sterile, pyrogen-free sodium hyaluronate solution.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eCOMPOSITION: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e1 GO-ON® prefilled syringe contains 2.5 ml of a 1% sodium hyaluronate solution as well as sodium chloride, sodium monohydrogen phosphate, sodium dihydrogen phosphate, and water for injection purposes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003ePROPERTIES: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSodium hyaluronate is a natural, high-molecular-weight polysaccharide composed of a linear chain of disaccharide units made up of sodium glucuronate and N-acetylglucosamine. Sodium hyaluronate is present in many tissues of the human body and is the main component of synovial fluid, where it occurs in high concentrations. It plays an important role as a joint lubricant in coordinating the physical and mechanical interactions between adjacent tissues. As a viscoelastic support material, it also maintains the spacing between tissues. Sodium hyaluronate preparations can have different molecular weights but share the same chemical structure. GO-ON® is a 1% sodium hyaluronate solution obtained from Streptococcus equi through fermentation processes and subsequent purification.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eINDICATIONS: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGO-ON is indicated as a viscoelastic supplementation of the synovial fluid in the knee. Viscosupplementation is recommended for patients with normal weight or moderate overweight with symptomatic mild to moderate knee OA whose condition cannot be sufficiently improved by non-pharmacological treatment and analgesics\/NSAIDs or who cannot take analgesics\/NSAIDs. The product acts as a lubricant and mechanical support and is suitable for treating symptoms\u003cbr\u003eof osteoarthritis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eCONTRAINDICATIONS: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGO-ON® must not be used in patients with a history of hypersensitivity to any of the product's components or in inflammatory joint diseases such as rheumatoid arthritis or ankylosing spondylitis. Since the safety of this product has not been established in children, pregnant, or breastfeeding women, it must not be used in these patients. Recognized contraindications for intra-articular hyaluronic acid injection include active joint infections, bacteremia, and diseases of the overlying skin. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWARNINGS AND PRECAUTIONS: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis product may only be used by doctors. In particular, the doctor should have training as an orthopedist, rheumatologist, or physiatrist. | \u003c\/span\u003e\u003cspan\u003eRecommendations regarding injection techniques: - Ensure that the joint shows no clinical signs of acute inflammation (heat, redness, swelling) before injection of GO-ON®; \u003c\/span\u003e\u003cspan\u003e| \u003c\/span\u003e\u003cspan\u003e- If necessary, removal of excess synovial fluid (due to joint effusion) before injection; \u003c\/span\u003e\u003cspan\u003e| \u003c\/span\u003e\u003cspan\u003e- Use of aseptic technique to avoid contamination and infection at the injection site. Do not use if the blister packaging has been opened and\/or damaged. The product must not be used after the expiration date indicated on the box. The product should be kept out of reach of children. In patients with osteoarthritis, this preparation may worsen an existing local inflammation. Therefore, it is advisable to administer the product only after the local symptom has been alleviated.\u003cbr\u003eIn rare cases, local pain may occur after administration of the product.\u003cbr\u003eTo avoid pain after the injection, instructions should be given,\u003cbr\u003ekeeping the site as still as possible for 2-6 hours after the injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThe product must be injected strictly into the intra-articular area, as otherwise it may cause pain. Avoid injections into blood vessels or surrounding tissue! The preparation should be administered with caution to patients who have frequently shown hypersensitivity to medications, and the patient should remain under clinical observation for at least 1 hour after the injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSIDE EFFECTS: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn rare cases, some patients develop a skin rash, such as urticaria and pruritus. In such cases, administration should be discontinued and the patient treated accordingly. Pain (mainly transient pain after administration), swelling and effusions, as well as infections at the injection site, have been reported only rarely. Patients rarely complain of redness, warmth, and a feeling of heaviness at the injection site. Shock has been reported only in rare cases. Anaphylactic reactions may occur. In this case, administration should be stopped, the patient closely monitored, and appropriate treatment carried out. Other reported incidents include reactive arthritis, necrosis of the M. vastus medialis and skin, pulmonary embolism, lesions, torn meninges with injections into facet joints, skin rash, deep vein inflammation, general fatigue, high blood pressure, cardiac arrhythmias, knee inflammations, knee cysts, allergic reactions, and surgical interventions. After injection of GO-ON®, local side effects may occur in the treated joint, such as pain, warmth, redness, and\/or swelling and effusion. These side effects can be alleviated by applying an ice pack to the treated joint for \u003c\/span\u003e\u003cspan\u003ecan be reduced by 5 to 10 minutes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eINTERACTIONS WITH OTHER MEDICATIONS: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThere is a known incompatibility between sodium hyaluronate and quaternary ammonium salts, such as benzalkonium chloride, which can be used as skin disinfectants. Therefore, GO-ON® must never come into contact with such products or with medical or surgical devices treated with these types of products, as hyaluronic acid may precipitate in their presence. No incompatibilities (interactions) with other solutions for intra-articular administration have been observed with GO-ON® so far. During the first days of treatment, the simultaneous administration of oral analgesics or anti-inflammatory drugs may prove beneficial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eDOSAGE AND ADMINISTRATION: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGO-ON should be injected into the affected joint a total of 5 times at weekly intervals. Depending on the severity of the joint disease, the effect of a course of five treatments can last up to 6 months.\u003cbr\u003eTreatment cycles can be repeated if necessary. In the case of effusion in a joint, it is recommended to puncture it, immobilize the joint, apply an ice pack, and\/or administer corticosteroids by intra-articular injection. Treatment with GO-ON® can be repeated 2-3 days later. Remove the syringe from the blister, take off the rubber stopper, attach a suitable sterilized needle (e.g., 19 or 21 G), and secure it with a slight twist. When attaching the needle and removing the needle cover, be careful not to tighten it too much or lever it excessively. Before injection, press out excess air from the syringe. GO-ON should be administered separately and not mixed with other substances before injection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eFEATURES AND MODE OF ACTION: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe viscoelastic synovial fluid, due to its hyaluronic acid content, is found in all synovial joints, especially \u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-mce-style=\"font-size: 0.875rem;\"\u003ein the large joints, which are subjected to considerable stress due to body weight. Here, synovial fluid serves as joint lubricant and shock absorber, ensuring normal, pain-free joint movements. Furthermore, synovial fluid supplies nutrients to the joint cartilage. Degenerative joint diseases such as osteoarthritis are associated with a significant reduction in the viscosity of synovial fluid, which impairs its lubricating and shock-absorbing function. As a result, mechanical joint stress and the loss of joint cartilage tissue increase so significantly \u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-mce-style=\"font-size: 0.875rem;\"\u003ethat pain and functional limitations occur in the affected joints \u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-mce-style=\"font-size: 0.875rem;\"\u003eIt has been proven that the quality improvement of synovial fluid caused by intra-articular injection of sodium hyaluronate preparations also improves its viscoelastic properties. This promotes its function as a lubricant and shock absorber, which reduces mechanical joint stress. This leads to pain relief and improved joint mobility. This effect can last more than six months after a treatment cycle of five intra-articular injections.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003ePACKAGING: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGO-ON® is supplied as a prefilled syringe with 2.5 ml (25 mg) sodium hyaluronate solution. The product was sterilized by steam inside the blister. One package contains\u003cbr\u003e1 syringe.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSHELF LIFE: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e3 years\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSTORAGE: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStore at 2°C to 25°C.\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eSYMBOLS ON THE PACKAGING: \u003c\/span\u003e\u003cspan\u003e1: \u003c\/span\u003e\u003cspan\u003eBatch number | \u003c\/span\u003e\u003cspan\u003e2: \u003c\/span\u003e\u003cspan\u003eUse by |\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e3: \u003c\/span\u003e\u003cspan\u003eSingle use only | \u003c\/span\u003e\u003cspan\u003e4: \u003c\/span\u003e\u003cspan\u003eObserve instructions for use. | \u003c\/span\u003e\u003cspan\u003e5: \u003c\/span\u003e\u003cspan\u003eSterile by moist heat | \u003c\/span\u003e\u003cspan\u003e6: \u003c\/span\u003e\u003cspan\u003eStorage temperature 2-25°C | \u003c\/span\u003e\u003cspan\u003e7: \u003c\/span\u003e\u003cspan\u003eManufacturer | \u003c\/span\u003e\u003cspan\u003e8: \u003c\/span\u003e\u003cspan\u003eDo not use if the packaging is damaged! | \u003c\/span\u003e\u003cspan\u003e9: \u003c\/span\u003e\u003cspan\u003eKeep dry | \u003c\/span\u003e\u003cspan\u003e10: \u003c\/span\u003e\u003cspan\u003eDo not re-sterilize\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eUSE OF GO-ON®: \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e❶ \u003c\/span\u003e\u003cspan\u003eRemove the syringe from the container. If the product is stored in the refrigerator (see storage conditions), take it out twenty or thirty minutes before use. | \u003c\/span\u003e\u003cspan\u003e❷ \u003c\/span\u003e\u003cspan\u003eTurn and remove the rubber stopper. | \u003c\/span\u003e\u003cspan\u003e❸ \u003c\/span\u003e\u003cspan\u003eAttach a 19- or 21-gauge injection needle. When attaching the needle and removing the needle cap, be careful not to tighten too much or lever too hard, as this could break the syringe tip. | \u003c\/span\u003e\u003cspan\u003e❹ \u003c\/span\u003e\u003cspan\u003eThe syringe is ready for use. *Before administration, thoroughly disinfect the injection site. Do not use a disinfectant containing quaternary ammonium salts at the same time.\u003cbr\u003eReusing single-use products carries a potential infection risk for patients or users. Contamination of the unit can lead to injury, illness, or death of the patient.\u003cbr\u003ePlease dispose of GO-ON® according to local regulations.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eNOTE: \u003c\/span\u003e\u003cspan\u003eThe GO-ON® implant is considered safe in the magnetic resonance (MR) environment. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMANUFACTURER ACCORDING TO MEDICAL DEVICE REGULATIONS:\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eRottapharm Ltd.\u003c\/span\u003e\u003cspan\u003e, Damastown Industrial Park, Mulhuddart-Dublin 15, Ireland;\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e+353 1 8852 700\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eDISTRIBUTION FOR BELGIUM: \u003c\/span\u003e\u003cspan\u003eSee folding box\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eDISTRIBUTION FOR GERMANY: \u003c\/span\u003e\u003cspan\u003eSee folding box \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDISTRIBUTION FOR AUSTRIA\u003c\/span\u003e\u003cspan\u003eSee folding box\u003cbr\u003eThis instruction manual was last revised in 03\/2021 M1161A\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Viatris Healthcare GmbH","offers":[{"title":"Default Title","offer_id":47355879424340,"sku":"111","price":22.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0786\/8756\/8212\/files\/go-on-viatris-healthcare-gmbh-gelenkspritzen-stakonmed-987449.jpg?v=1772214420","url":"https:\/\/stakonmed.com\/products\/go-on-1-x-2-5-ml","provider":"StakonMed","version":"1.0","type":"link"}