{"product_id":"recosyn-m-d-n-1-x-1-ml","title":"Recosyn m.d.N  1x 1.0 ml","description":"\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/stakonmed.de\/collections\/recosyn\" title=\"Recosyn | Gelenkspritzen | StakonMed\"\u003e\u003cspan\u003eRecosyn\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e® \u003c\/span\u003e\u003cspan\u003em.d. N\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSodium hyaluronate intra-articular\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDescription\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe product contains a prefilled syringe with hydrogel made from highly purified sodium hyaluronate obtained by bacterial fermentation without genetic modifications, with high molecular weight, used to improve viscosity in intra-articular connective tissue. It has undergone steam sterilization for injectable products and is non-pyrogenic.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe product contains 1 ml aqueous, physiological phosphate buffer solution with 10 mg sodium \u003c\/span\u003e\u003cspan\u003ehyaluronate. The sodium hyaluronate hydrogel is in a weak, sterile \u003c\/span\u003e\u003cspan\u003elen, isotonic and apyrogenic phosphate-buffered saline solution with a pH of 7.2 (6.8 – 7.4) in sufficient volume for injection. The fill volume of a prefilled syringe is 1 ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe chemical components are listed in the table on the right (weight per volume as mg substance per 1 ml hydrogel).\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eProperties and mode of action\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003eEssential component of healthy synovial fluid is the widespread glycosami\u003c\/span\u003e\u003cspan\u003enoglycan hyaluronic acid. This natural biopolymer provides viscoelasticity and, thanks to its lubricating and shock-absorbing properties, enables pain-free physiological movements; it also supplies nutrients to the cartilage. The \u003c\/span\u003e\u003cspan\u003eRecosyn\u003c\/span\u003e\u003cspan\u003e® \u003c\/span\u003e\u003cspan\u003em.d. N \u003c\/span\u003e\u003cspan\u003econtained sodium hyaluronate is a salt of hyaluronic acid.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eIndications\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003ePain and limitation of joint mobility in degenerative changes of the knee joint and other synovial joints, including osteoarthritis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eContraindications\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThe product must not be used in patients\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e- with known hypersensitivity to any of the ingredients\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e- with inflammation in the joint\u003cbr\u003e- with septic arthritis\u003cbr\u003e- with skin infections or skin diseases in the injection area\u003cbr\u003e- with natural or medication-induced coagulation disorders such as hemophilia\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eor when using anticoagulants such as Marcumar (phenprocoumon) or Coumadin (warfarin)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eSince there are no clinical data on the use of hyaluronic acid in children, pregnant or breastfeeding women, use in these patients is not recommended.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003ePrecautions\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003eSince septic arthritis can be a serious complication of treatment, please observe all precautions usually necessary for surgical procedures. Injections of the hydrogel must be administered precisely into the joint cavity; injections into blood vessels and surrounding tissue must be avoided.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDo not use if the prefilled syringe or sterile packaging is damaged.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe opened product must not be resterilized, resealed, or reused. It is intended for use by a single patient at a single treatment session.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePossible side effects\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNo adverse effects were observed in biocompatibility tests with the product. Local reactions such as pain, redness, warmth, and swelling may occur in the treated joint. These symptoms can be reduced by cooling the treated area with an ice pack for 5 to 10 minutes after injection. During the first days of treatment, the simultaneous oral intake of pain and anti-inflammatory medications (NSAIDs) may be beneficial. If severe pain or inflammation occurs, treatment should be discontinued. Management of adverse reactions should only be carried out under the supervision of the treating physician. Immediately after the injection, strenuous physical activity should be avoided, and other instructions from the doctor should be followed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMedical professionals should inform the patient\u003cbr\u003e- about possible adverse events related to the product.\u003cbr\u003e- that the patient must inform a doctor of any adverse event or complication.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003ePharmacological and chemical interactions\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eSo far, there are no data on the incompatibility of the product with other solutions for intra-articular use.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThere is a chemical incompatibility between sodium hyaluronate and quaternary ammonium compounds such as benzalkonium chloride, which can lead to crystalline precipitation. Therefore, this product must never come into contact with surgical instruments or other products containing these compounds, or with solutions rinsed with quaternary ammonium compounds used as biocidal preservatives.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDosage, type, and duration of use\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRemove the prefilled syringe from its packaging. Remove the protective cap from the Luer-Lock thread. Screw a suitable sterile injection needle onto the syringe. The use of a single-use needle is recommended. Air should be evacuated from the needle before injection. The skin area intended for injection must be cleaned with an appropriate topical antiseptic. In the case of joint effusion, it is recommended to first reduce the effusion by aspiration before injecting the gel and to examine it for bacterial etiology. The hydrogel can be injected intra-articularly 1 to 5 times at intervals determined by the physician. The beneficial effects of a treatment last at least 6 months. Treatment cycles can be repeated if necessary.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnused product must be disposed of.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eDosage form\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eOne box with a prefilled syringe of 1 ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eShelf life\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThe product must not be used after the expiration date. The expiration date (month\/year) is printed on the syringe blister and on the carton.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eStorage instructions\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe product should be stored dry between 2° and 25°C and protected from light and impact in the original packaging. Accordingly, observe the warning symbols on the packaging.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eKeep the product out of reach of children.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eRecommended user group\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eIntended exclusively for use by physicians.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eFor single use only. Do not resterilize. Do not use syringes, needles, or hydrogel from open or damaged packaging or attempt to reseal packaging. Syringe contents are non-toxic and non-flammable.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhen using a product from damaged packaging or reusing it on other patients or the same patient at a different time, the intended properties and sterility are not guaranteed. Otherwise possible \u003c\/span\u003e\u003cspan\u003eTransmission of material contamination and pathogens from the environment, the clinical \u003c\/span\u003e\u003cspan\u003eUse on another area or (other) patients could lead to health complications. Resealing or resterilization does not constitute an allowed or guaranteed restoration of the usable condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnused syringes and their contents are not infectious and can be disposed of before or after the expiration date, observing national and local regulations. Used syringes and needles must be treated as epidemiologically hazardous waste and national and local regulations for safe use and disposal must be followed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInformation status 06\/2021\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003cspan style=\"font-size: 0.875rem;\"\u003eIntended exclusively for use by physicians.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Recordati Pharma GmbH","offers":[{"title":"Default Title","offer_id":47355880538452,"sku":"130","price":21.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0786\/8756\/8212\/files\/recosyn-md-n-recordati-pharma-gmbh-gelenkspritzen-stakonmed-883596.jpg?v=1772215360","url":"https:\/\/stakonmed.com\/products\/recosyn-m-d-n-1-x-1-ml","provider":"StakonMed","version":"1.0","type":"link"}